Spongebob and Patrick blow bubbles, and they soon get bored. Spongebob suggests they "spice up" their bubble blowing. Patrick is struck with an idea, and takes out a bottle of hot sauce. He dunks his wand into the bottle and blows a spicy bubble into Spongebob's eyes. Spongebob screams as his eyes glow red and disintegrate, then grow back. Then he blows a spicy bubble into Patrick's eyes, doing the same thing to him. They burn each others' eyes repeatedly. Meanwhile, Squidward is clipping his likeness into a Bonsai. Just as he's about to clip off a straggler leaf, they scream, and he lops off the entire head. The beheaded bonsai requests that Squidward avenge it. Squidward yells at them out the window, but they blow spicy bubbles at him, burning him to ashes.
Spongebob and Patrick go to Sandy's treedome, where she is outside fixing an airtank. They tell her about their new discovery, with Patrick convinced he's a genius for his new idea, even thinking he's smarter than Sandy. She tells them she's busy fixing a clog in the airtank. Patrick suggests she breathes air like a "smart person", and she explains land creatures need air. Patrick simply dismisses her as stupid. Spongebob tries to help clear the blockage by blowing spicy bubbles onto the airtank, but it melts. Water rushes into the treedome, filling it completely. Sandy only has a little bit of air left in her suit, so she goes to her submarine which has enough air to go to the surface and replenish the air supply for her treedome. However, Spongebob opens the door and water rushes in. Sandy tasks Spongebob with driving the submarine to the surface, as the low amount of air is making her woozy. As they make their way to the surface, the lack of air in Sandy's suit causes her to act strange (such as trying to lick Patrick). When they reach the top, a delirious Sandy suddenly gets a craving for a Krabby Patty and drives the submarine through the roof of the Krusty Krab. Her suit's air supply is finally depleted and she removes her helmet. She takes a patron's Krabby Patty and eats it.
Spongebob and Patrick try to help Sandy get air, and they notice air bubbles from the submarine on the ceiling. Spongebob uses a line of straws to reach them. Patrick sucks them in, then blows into Sandy's mouth. Spongebob suggests Mr. Krabs might have air in him, telling him Squidward says he's "full of hot air" (which Squidward nervously denies). Mr. Krabs says he indeed has an air bubble or two and pulls in his eyestalks so Sandy can breathe them in. Pearl comes in, and Spongebob suggests she could help give air to Sandy. Pearl agrees, saying "I guess we mammals gotta stick together". Sandy puts her mouth over Pearl's blowhole, and Pearl exhales, inflating her like a balloon. Spongebob figures he can go to the surface and fill a bubble with air. Using an oxygen tank, he rockets to the surface, creates a giant air-filled bubble, and puts it into the treedome.
Sandy wakes up in the treedome with Spongebob and Patrick. Spongebob explains that he saved her with bubbles and she remembers that it was bubbles which caused all the trouble in the first place. Sandy tells them not to blow bubbles around her treedome anymore, but it turns out Spongebob already blew one giant bubble around the treedome, which lifts it away.
'Pearl' told that mammals has to be togethder so 'Sandy' and Pearl are mammals and so that means sometimes they hang out each other.
This is the second time the title card was the close-up of an object from an episode. This title card was the "hay in the needle stack" scene from Pre-Hibernation Week. The first time was in No Nose Knows with the Big Stink Ball.
This is the third time something gets into a character's eyes and burns them. The first was Mr. Krabs with salt in Krab Borg and the second was SpongeBob with bubble solution in Krabby Land.
This is another instance in which Sandy is treated like an idiot. The first was in Squirrel Jokes, and the second was in The Krabby Kronicle.
Despite Squidward calling his trimmed plant a bonsai, it is in fact a topiary. A bonsai is a miniaturized tree, while a topiary is a shrub, bush, or tree trimmed in a certain shape (in this case, Squidward's head).
Usually when Sandy's Treedome filled up with water, it sucks in all the Bikini Bottomites and drains the sea (as seen in Squirrel Jokes and A Flea in Her Dome). This happens again, though neither event happens this time.
